The combinations just haven't worked for us. My husband has tried several, but after the last one, he decided that Nuvigil would suffice for now. While the Prozac/Nuvigil combo gave my husband a manic amount of energy, it also made it even more difficult for him to sleep, and gave him frequent headaches.
Although the Nuvigil isn't the perfect solution, it is working well with limited side effects - which is about all one can ask for, right? Especially considering the side effects that are possible with Nuvigil.
(from the official site:)
For now, Nuvigil is keeping my husband awake when he wants to be, and his Cataplexy seems to have let up somewhat. Until it stops working, just we'll be content with that.
Incidentally, I wanted to mention something that has been immensely helpful to our family while my husband is out of work. Without health insurance, affording Nuvigil would be impossible for us. After contacting the Cephalon Cares Foundation, they have awesomely provided my husband with the medication he needs at no cost. In case your loved one needs Nuvigil but can't currently afford it, I'd highly recommend contacting them to see what they can do for you.